(6)Pediatric Neurology Units of Panaxia Medical Devices and Pharmaceuticals, Tel Aviv, Israel. (7)Pediatric Neurology Units of Medical Cannabis Unit, Ministry of Health, Tel Aviv, Israel. PURPOSE: To describe the experience of five Israeli pediatric epilepsy clinics treating children and adolescents diagnosed as having intractable epilepsy with a regimen of medical cannabis oil. The last three years have witnessed growing interest among the medical community, parent groups and media in the use of enriched CBD medical cannabis and pure CBD in intractable pediatric epilepsy. Based on anecdotal reports and parental pressure, marijuana is currently licensed for seizures or epilepsy in 14 states in the US . Seizures are a symptom of epilepsy, but not all people who have seizures have epilepsy. About one in every one-hundred people will have an unprovoked seizure in their lifetime. About 4% of people will develop epilepsy in their life. Four of the eight CBD subjects remained almost seizure-free throughout the experiment. And three others demonstrated partial improvement. Consequently, cannabidiol was only ineffective in one patient. In 2013, the Journal of Epilepsy and Behavior published a clinical study on CBD epilepsy treatment. Through a Facebook survey, 19 epileptic. Interest has been steadily growing in the use of cannabis‐based treatments for pediatric epilepsy, 7 partly owing to media reports of successful cases. 8 Nine‐delta‐tetrahydrocannabinol (THC) and cannabidiol (CBD) have received the greatest attention as potential antiepileptic agents. In practice, the psychoactive properties of THC may. Bio CBD PLUS - The Most Effective CBD on the Market! CBD Tincture - Enjoy the benefits of our full spectrum CO2 extracted CBD; CBD Capsules offer a convenient way to take CBD on the go or for those who may not like the taste of our tinctures. Advisors to the Food and Drug Administration have found a generally favorable benefit-risk profile for cannabidiol oil solution in the treatment of two forms of severe pediatric seizure disorders. The drug is under expedited review by the agency. CBD, or CBD oil, is short for cannabidiol, an element found in the Cannabis Sativa plant. It is one of the non-psychoactive ingredients in cannabis. It binds to a system in our body called the endocannabinoid system. This system is one of the newest discoveries in medicine, and is being shown to play a huge role in our health and wellbeing, including during pregnancy and while nursing. This system has until recently has been neglected. As you can see, CBD, with its multiple mechanisms of action, acts at multiple targets in the brain. This is why we think it works well for epilepsy. Since CBD does not activate the cannabinoid receptor the way THC does, it does not cause tolerance, and as it is not psychoactive, it is an ideal compound for pediatric patients. However, placebo controlled trials of Epidiolex for Dravet and Lennox-Gastaut syndrome are now in process. Consequently higher quality medical evidence surrounding the use of CBD for the treatment of pediatric epilepsy syndromes will be forthcoming.